Jeonbuk National University Animal Medical Center iksan, Cholla-bukto, Republic of Korea
Abstract: Background
According to a study conducted in the United States, myxomatous mitral valve disease(MMVD) is the most common acquired cardiovascular disease in dogs. It can be suspected by cardiac murmur or chest radiography, and the golden standard for diagnosis is evaluation of cardiac morphologic changes by echocardiography.
Hypothesis/objectives To identify the diagnostic value of pulmonary vein to pulmonary artery ratio (PA/PV) measurement with echocardiography for dogs diagnosed as MMVD. Animals A total of 75 client-owned dogs who visited Jeonbuk National University Animal Medical Center from October 2020 and October 2022 were retrospectively studied It was approved by IACUC. Methods The PA/PV was measured using bi-dimensional mode in the right parasternal long axis four chamber view. Results The PV/PA in each group: control (1.08 ± 0.22), stage B1 (1.32 ± 0.30), stage B2 (2.06 ± 0.72), stage C (2.94 ± 1.01). Using One-way ANOVA analysis, it was confirmed that the PV/PA increased significantly as the MMVD stage progressed (P < 0.001). Additionally, PV/PA was higher in the congested heart failure (CHF) group when compared with the no-CHF group (P < 0.001). Conclusion and clinical importance In conclusion, as the severity of MMVD increased, PV/PA significantly increased, and it was confirmed that there was a positive correlation with conventional indicators. The PV/PA measurement has advantages of being easy and simple to evaluate compared to existing echocardiography indices. However, additional studies with various variables controlled are required, and more data should be accumulated to support the reliability of the study.