Asst Professor of Pediatrics Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States
Presentation Description / Summary: DIscussing how early-life gut commensal microbes educate the immune system. We developed a gnotobiotic mouse model of the early-life microbiome (called PedsCom) to study host-commensal interaction during a critical early-life window of immune ontogeny. Our current research leverages PedsCom to develop microbiota-based approaches to prevent autoimmune diabetes.
Learner Outcomes: Understand how commensal microbes impact immune system development. New gnotobiotic tools to study host-commensal interaction during early life and beyond
Learning Objectives:
Upon completion, participant will be able to understand how early life commensal microbes impact immune system development.
Upon completion, participant will be able to describe the value of using gnotobiotic models to study host development
Upon completion, participant will be able to understand how early life commensal microbes impact autoimmune diabetes.